Chimica | CHEMISTRY OF BIOMIMETIC COMPOUNDS

cod. 0522300047

CHEMISTRY OF BIOMIMETIC COMPOUNDS

	0522300047
	DEPARTMENT OF CHEMISTRY AND BIOLOGY "ADOLFO ZAMBELLI"
	EQF7
	CHEMISTRY
	2020/2021

CURRICULUM BIOMOLECULAR CHEMISTRY

	YEAR OF COURSE 2
	YEAR OF DIDACTIC SYSTEM 2016
	SECONDO SEMESTRE

TEACHING UNITS

SSD	CFU	HOURS	ACTIVITY	TYPE OF ACTIVITY
CHIM/06	5	40	LESSONS	SUPPLEMENTARY COMPULSORY SUBJECTS
CHIM/06	1	12	EXERCISES	SUPPLEMENTARY COMPULSORY SUBJECTS

	Objectives
	THE AIM OF THIS COURSE IS TO PROVIDE AN OVERVIEW OF THE CORE CONCEPTS IN SUPRAMOLECULAR CHEMISTRY WHICH, NON-COVALENT BONDING, HOST-GUEST CHEMISTRY, SELF-ASSEMBLY SYSTEMS AND ARTIFICIAL MOLECULAR MACHINES. IN ADDITION THE SUPRAMOLECULAR CHEMISTRY OF THE BIOLOGICAL SYSTEMS IS ILLUSTRATED AND THE ANALYTHICAL AND SPECTROSCOPIC METHODS UTILIZED TO CHARACTERIZE THE SUPRAMOLECULAR SYSTEMS ARE INTRODUCED. AFTER THE COURSE THE STUDENT IS ABLE TO CARRY OUT THE DESIGN OF BIOMIMETIC SYSTEMS WITH SPECIFIC PROPERTIES AND FUNCTIONS.

THE AIM OF THIS COURSE IS TO PROVIDE AN OVERVIEW OF THE CORE CONCEPTS IN SUPRAMOLECULAR CHEMISTRY WHICH, NON-COVALENT BONDING, HOST-GUEST CHEMISTRY, SELF-ASSEMBLY SYSTEMS AND ARTIFICIAL MOLECULAR MACHINES. IN ADDITION THE SUPRAMOLECULAR CHEMISTRY OF THE BIOLOGICAL SYSTEMS IS ILLUSTRATED AND THE ANALYTHICAL AND SPECTROSCOPIC METHODS UTILIZED TO CHARACTERIZE THE SUPRAMOLECULAR SYSTEMS ARE INTRODUCED. AFTER THE COURSE THE STUDENT IS ABLE TO CARRY OUT THE DESIGN OF BIOMIMETIC SYSTEMS WITH SPECIFIC PROPERTIES AND FUNCTIONS.

	Prerequisites
	THE MAIN PREREQUISITES CONCERN THE CONCEPTS OF GENERAL, INORGANIC AND ORGANIC CHEMISTRY, AS WELL AS THE ACQUAINTANCE WITH THE USE OF THE SYMBOLOGY OF ORGANIC CHEMISTRY AND BASIC STEREOCHEMISTRY. FURTHERMORE, IT IS REQUIRED THE KNOWLEDGE OF BASIC ORGANIC SYNTHESIS AND SPECTROMETRIC ORGANIC TECHNIQUES.

	Contents
	CHEMICAL SECONDARY INTERACTIONS IN BIOLOGICAL SYSTEMS. EXAMPLES DERIVED FROM DNA, RNA, PROTEINS, ENZYMES. INTERMOLECULAR INTERACTIONS, STRUCTURAL AND ENERGETICAL ASPECTS. MOLECULAR RECOGNITION THERMODYNAMIC AND KINETIC ASPECTS. CLASSES OF COMMON HOSTS. CATIONIC, ANIONIC, MOLECULAR RECOGNITION AND ITS APPLICATIONS. SUPRAMOLECULAR CATALYSIS. SELF-ASSEMBLY. CRYSTAL ENGINEERING. SUPRAMOLECULAR DEVICES.

Contents

CHEMICAL SECONDARY INTERACTIONS IN BIOLOGICAL SYSTEMS. EXAMPLES DERIVED FROM DNA, RNA, PROTEINS, ENZYMES. INTERMOLECULAR INTERACTIONS, STRUCTURAL AND ENERGETICAL ASPECTS. MOLECULAR RECOGNITION THERMODYNAMIC AND KINETIC ASPECTS. CLASSES OF COMMON HOSTS. CATIONIC, ANIONIC, MOLECULAR RECOGNITION AND ITS APPLICATIONS. SUPRAMOLECULAR CATALYSIS. SELF-ASSEMBLY. CRYSTAL ENGINEERING. SUPRAMOLECULAR DEVICES.

	Teaching Methods
	•DIRECT LESSONS •PROJECT DESIGN

	Verification of learning
	•ORAL EXAMINATIONS

	Texts
	J. W. STEED AND J. L. ATWOOD, SUPRAMOLECULAR CHEMISTRY, WILEY 2000. J.-M. LEHN , SUPRAMOLECULAR CHEMISTRY: CONCEPTS AND PERSPECTIVES, VCH 1995. P. D. BEER, P. A. GALE, D. K. SMITH SUPRAMOLECULAR CHEMISTRY. J. W. STEED AND J. L. ATWOOD, ENCYCLOPEDIA OF SUPRAMOLECULAR CHEMISTRY, MARCEL DEKKER 2004. COMPREHENSIVE SUPRAMOLECULAR CHEMISTRY II, 2ND ED., ELSEVIER, 2017, ED. JERRY ATWOOD, APPUNTI DALLE LEZIONI. LESSON “POWER-POINT” PRESENTATIONS.

Texts

J. W. STEED AND J. L. ATWOOD, SUPRAMOLECULAR CHEMISTRY, WILEY 2000.
J.-M. LEHN , SUPRAMOLECULAR CHEMISTRY: CONCEPTS AND PERSPECTIVES, VCH 1995.
P. D. BEER, P. A. GALE, D. K. SMITH SUPRAMOLECULAR CHEMISTRY.
J. W. STEED AND J. L. ATWOOD, ENCYCLOPEDIA OF SUPRAMOLECULAR CHEMISTRY, MARCEL DEKKER 2004.
COMPREHENSIVE SUPRAMOLECULAR CHEMISTRY II, 2ND ED., ELSEVIER, 2017, ED. JERRY ATWOOD,
APPUNTI DALLE LEZIONI.
LESSON “POWER-POINT” PRESENTATIONS.