Chimica | BIOLOGICALLY ACTIVE NATURAL PRODUCTS

cod. 0522300048

BIOLOGICALLY ACTIVE NATURAL PRODUCTS

	0522300048
	DEPARTMENT OF CHEMISTRY AND BIOLOGY "ADOLFO ZAMBELLI"
	EQF7
	CHEMISTRY
	2020/2021

CURRICULUM BIOMOLECULAR CHEMISTRY

	YEAR OF COURSE 2
	YEAR OF DIDACTIC SYSTEM 2016
	SECONDO SEMESTRE

TEACHING UNITS

	SSD	CFU	HOURS	ACTIVITY	TYPE OF ACTIVITY
	CHIM/06	6	48	LESSONS	SUPPLEMENTARY COMPULSORY SUBJECTS

	Objectives
	THE TARGET OF THE COURSE IS TO GIVE A BASIC KNOWLEDGE ON THE MOST COMMON BIOGENETIC PATHWAYS RELATIVE TO SECONDARY METABOLITES OF A VARIETY LIVING ORGANISM ( MICROORGANISMS, PLANTS AND ANIMALS). AFTER SUCCESSFUL COMPLETION OF THIS COURSE, STUDENTS SHOULD BE ABLE TO UNDERSTAND THE ISSUES OF NATURAL PRODUCT CHEMISTRY, RECOGNIZE STRUCTURE AND MOLECULAR CLASSIFICATION OF A REPRESENTATIVE NUMBER OF COMPOUNDS BELONGING TO THE MAIN CLASSES OF NATURAL PRODUCTS, KNOW THE RELEVANCE OF SELECTED NATURAL COMPOUNDS, THEIR BIOGENESIS, AND SOME CHEMICAL ELABORATION. STUDENTS ARE SUPPOSED TO BE ABLE TO PRESENT, IN A CLEAR AND RIGOROUS MANNER THE MAIN TOPICS CONTAINED IN THE COURSE

THE TARGET OF THE COURSE IS TO GIVE A BASIC KNOWLEDGE ON THE MOST COMMON BIOGENETIC PATHWAYS RELATIVE TO SECONDARY METABOLITES OF A VARIETY LIVING ORGANISM ( MICROORGANISMS, PLANTS AND ANIMALS). AFTER SUCCESSFUL COMPLETION OF THIS COURSE, STUDENTS SHOULD BE ABLE TO UNDERSTAND THE ISSUES OF NATURAL PRODUCT CHEMISTRY, RECOGNIZE STRUCTURE AND MOLECULAR CLASSIFICATION OF A REPRESENTATIVE NUMBER OF COMPOUNDS BELONGING TO THE MAIN CLASSES OF NATURAL PRODUCTS, KNOW THE RELEVANCE OF SELECTED NATURAL COMPOUNDS, THEIR BIOGENESIS, AND SOME CHEMICAL ELABORATION. STUDENTS ARE SUPPOSED TO BE ABLE TO PRESENT, IN A CLEAR AND RIGOROUS MANNER THE MAIN TOPICS CONTAINED IN THE COURSE

	Prerequisites
	GOOD KNOWLEDGE OF FUNCTIONAL GROUPS AND REACTIVITY IN ORGANIC CHEMISTRY IS STRONGLY REQUIRED. THEREFORE, TO ACCESS THE FINAL EXAMINATION, IT IS NECESSARY TO PASS BOTH ORGANIC CHEMISTRY I AND II EXAMS.

	Contents
	THE MOST IMPORTANT CLASSES OF NATURAL ORGANIC COMPOUNDS WILL BE ANALYZED IN TERMS OF CHEMICAL STRUCTURE, BIOGENESIS, STEREOCHEMISTRY, PHYSICO-CHEMICAL PROPERTIES, AND BIOACTIVITY. PRIMARY AND SECONDARY METABOLISM. MAIN METHODOLOGIES USED IN THE STUDY OF A BIOSYNTHESIS. BIOSYNTHETIC PATHWAYS OF FATTY ACIDS AND POLIKETIDES, BIOSYNTHETIC PATHWAYS OF SHIKIMIC ACID DERIVATIVES, BIOSYNTHETIC PATHWAYS OF ISOPRENOIDS AND STEROLS. INTRODUCTION ON THE BIOSYNTHESIS OF ALKALOIDS. INDUSTRIAL APPLICATIONS OF NATURAL PRODUCTS.

Contents

THE MOST IMPORTANT CLASSES OF NATURAL ORGANIC COMPOUNDS WILL BE ANALYZED IN TERMS OF CHEMICAL STRUCTURE, BIOGENESIS, STEREOCHEMISTRY, PHYSICO-CHEMICAL PROPERTIES, AND BIOACTIVITY.
PRIMARY AND SECONDARY METABOLISM. MAIN METHODOLOGIES USED IN THE STUDY OF A BIOSYNTHESIS.
BIOSYNTHETIC PATHWAYS OF FATTY ACIDS AND POLIKETIDES,
BIOSYNTHETIC PATHWAYS OF SHIKIMIC ACID DERIVATIVES,
BIOSYNTHETIC PATHWAYS OF ISOPRENOIDS AND STEROLS.
INTRODUCTION ON THE BIOSYNTHESIS OF ALKALOIDS.
INDUSTRIAL APPLICATIONS OF NATURAL PRODUCTS.

	Teaching Methods
	LESSONS CONSIST IN ORAL SESSIONS THAT INCLUDE PRESENTATION OF EXAMPLES BY THE CURRENT LITERATURE AND DISCUSSIONS.

	Verification of learning
	THE AIM OF THE FINAL EXAM IS TO CHECK THAT THE LEARNING OUTCOMES HAVE BEEN ACHIEVED. FORMATIVE ASSESSMENT IS BY ORAL EXAMINATION COMPRISING QUESTIONS AND DISCUSSION ABOUT THE CONTENT OF THE TEACHING COURSE. THE ABILITY TO COMMUNICATE THE TOPICS WILL BE ALSO ASSESSED. THE RESULT OF THE EXAM IS MARKED IN THIRTIETH. A MINIMUM OF EIGHTEEN THIRTIETH IS REQUIRED AS A THRESHOLD.