BIOCHIMICA DEL MOVIMENTO

Scienze delle Attività Motorie, Sportive e dell'Educazione Psicomotoria BIOCHIMICA DEL MOVIMENTO

4412500053
DIPARTIMENTO DI SCIENZE UMANE, FILOSOFICHE E DELLA FORMAZIONE
EQF6
SCIENZE DELLE ATTIVITA' MOTORIE, SPORTIVE E DELL'EDUCAZIONE PSICOMOTORIA
2022/2023

OBBLIGATORIO
YEAR OF COURSE 1
YEAR OF DIDACTIC SYSTEM 2017
SPRING SEMESTER
CFUHOURSACTIVITY
636LESSONS


Objectives
The training objectives aim at the acquisition of knowledge relating to:
- the structure, function and metabolism of the main biomolecules (proteins, carbohydrates and lipids);
- the metabolic processes underlying the control of tissue homeostasis;
- the catabolic pathways involved in the energy metabolism of skeletal muscle during the course
physical activity.
Knowledge and understanding:
- chemical structure, levels of structural organization and of the chemical bonds involved, of the
biological properties and functions of proteins, carbohydrates and lipids, in particular proteins
involved in the bond with oxygen (myoglobin and hemoglobin) and in enzymatic catalysis
(enzymes);
- bioenergetic aspects of metabolism and main anabolic and catabolic pathways of glucose, acids
fats and amino acids;
- reactions and biochemical processes involved in ATP synthesis;
- this knowledge will allow the understanding of the energetic mechanisms activated in the muscle
skeleton during physical activity.
Ability to apply knowledge and understanding:
Autonomy of judgment:
- autonomous evaluation of the importance and role of biomolecules and their involvement in
processes underlying cell metabolism;
- evaluation of the biochemical processes activated during physical activity.
Communication skills:
the student will have acquired communication skills that will allow him to:
- to support and participate in discussions on biochemical aspects involved in issues within the scope
physical education;
- to present biochemical concepts and knowledge using appropriate scientific terminology.
Prerequisites
Basic knowledge of general and organic chemistry and general biology acquired
in upper secondary schools.
Contents
The contents of the course concern:
- the chemistry of living matter;
- the structure and function of the biomolecules involved in cellular metabolism and the main ones
mechanisms of regulation and metabolic correlation;
Oxidative catabolism: Krebs cycle: reactions, energy balance and regulation; and reactions
anaplerotic. The electron transport chain and oxidative phosphorylation, thermogenesis.
Lipid metabolism: structure, classification and function of lipids. Reserve fatty acids and lipids:
triglycerides. Membrane lipids: phospholipids. Cholesterol. Digestion and absorption of lipids.
Lipolysis and fatty acid catabolism: role of carnitine in intra-mitochondrial transport of
fatty acids and beta-oxidation. Energy balance. Synthesis and use of ketone bodies. Notes on
biosynthesis of fatty acids and on the metabolism of cholesterol and bile acids (9 hours).
Protein metabolism: degradation of proteins and amino acids: fate of the alpha group
amino acid (reactions of transamination and oxidative deamination) and of the carbonaceous skeleton
(glucogenic and ketogenic amino acids). Transport of the alpha-amino group from the tissues to the liver:
glutamine and glucose-alanine cycle. Urea cycle and regulation (3 hours).
Muscle contraction biochemistry: classification of muscle fibers. Energy systems:
lactacid and lactacid anaerobic mechanisms; aerobic mechanisms (3 hours).
- energy mechanisms activated during motor activity.
Teaching Methods
The course includes lectures (36 hours). In frontal lessons
the topics of the program will be treated, highlighting the conceptual aspects, the knowledge
structural and functional fundamentals, as well as their correlation. Students can take advantage of
an electronic version of the didactic material used in the lectures, which will be provided by
professor
Verification of learning
Learning assessment procedures: carrying out 3 tests to verify the knowledge of
which: the first at the beginning of the course, concerning the previous knowledge of general chemistry, chemistry
organic and cell biology; the second and third respectively in the middle and at the end of the course one at the end of the course
program topics covered in class. The written tests consist of 20 questions to be answered
multiple; the teacher reserves the right to reshape the number of questions on the basis of
student needs.
- The final exam: consists of a written test preparatory to the oral test. The written test is
consisting of 20 multiple choice questions on the topics covered in the program
teaching; the teacher reserves the right to reshape the number of questions on the
based on student needs.
- The oral exam consists in verifying the structural and functional knowledge of biomolecules,
of the main metabolic pathways; the following will be evaluated: exhibition contents, language properties e
the correlation between the different topics. The final vote will take into account both the score obtained at the
written test and the oral exam.
Texts
- Nelson D.L., Cox M.M. “Introduzione alla Biochimica di Lehninger” – Ed. Zanichelli;

-Di Giulio A., Fiorilli A., Stefanelli C. “Biochimica per le Scienze Motorie” – Ed. Ambrosiana.

Testi Utili per approfondimenti:
Nelson D.L., Cox M.M., “I principi di biochimica di Lehninger”, – Ed. Zanichelli;
- Baynes J.W., Dominiczak M.H. “Biochimica per le discipline biomediche” – Ed. Ambrosiana.
Qualsiasi altro testo recente di Biochimica conforme al programma.
  BETA VERSION Data source ESSE3 [Ultima Sincronizzazione: 2023-01-23]