Dentistry | C.I. BIOLOGIA

cod. 1060200004

C.I. BIOLOGIA

	1060200004
	DIPARTIMENTO DI MEDICINA, CHIRURGIA E ODONTOIATRIA "SCUOLA MEDICA SALERNITANA"
	EQF7
	DENTISTRY
	2020/2021

PERCORSO SHARED STUDY PATHWAY

	OBBLIGATORIO
	YEAR OF COURSE 1
	YEAR OF DIDACTIC SYSTEM 2015
	PRIMO SEMESTRE

TEACHING UNITS

	SSD	CFU	HOURS	ACTIVITY	TYPE OF ACTIVITY
1	C.I. BIOLOGIA - MOD. BIOLOGIA APPLICATA
	BIO/13	6	66	LESSONS	BASIC COMPULSORY SUBJECTS
2	C.I. BIOLOGIA - MOD. ODONTOSTOMATOLOGIA
	MED/28	1	11	LESSONS	COMPULSORY SUBJECTS, CHARACTERISTIC OF THE CLASS

PROFESSORS

	PAOLO REMONDELLI1 T Curriculum
	FEDERICA DI SPIRITO2 Curriculum

	Objectives
	DEMONSTRATE PROFICIENCY IN UNDERSTANDING CLASSICAL AND ADVANCED CONCEPTS IN CELL BIOLOGY - LEARN MOLECULAR MECHANISMS OF CELL FUNCTION AND MAINTENANCE OF CELLULAR COMPARTMENTS TO UNDERSTAND THE MOLECULAR BASIS OF HUMAN PATHOLOGIES - DEVELOP AN UNDERSTANDING OF THE SCIENTIFIC METHOD INCLUDING TO EVALUATE DATA ANALYSIS AND SCIENTIFIC LITERATURE AND HOW THESE METHODS CAN BE USED TO SOLVE CLINICAL PROBLEMS.

DEMONSTRATE PROFICIENCY IN UNDERSTANDING CLASSICAL AND ADVANCED CONCEPTS IN CELL BIOLOGY - LEARN MOLECULAR MECHANISMS OF CELL FUNCTION AND MAINTENANCE OF CELLULAR COMPARTMENTS TO UNDERSTAND THE MOLECULAR BASIS OF HUMAN PATHOLOGIES - DEVELOP AN UNDERSTANDING OF THE SCIENTIFIC METHOD INCLUDING TO EVALUATE DATA ANALYSIS AND SCIENTIFIC LITERATURE AND HOW THESE METHODS CAN BE USED TO SOLVE CLINICAL PROBLEMS.

	Prerequisites
	BASIC BIOCHEMISTRY AND PHISICS FOR THE STUDENTS IN DENTISTRY ACCORDING TO SECTION 11 OF THE PUBLISHED DIDACTIC GUIDELINES

	Contents
	LECTURES 1. PROPERTIES OF CELL MEMBRANES 2. AEROBIC RESPIRATION - BIOGENESIS AND MAINTAINANCE OF MITOCHONDRION - MITOCHONDRIAL DISEASES 3. INTRACELLULAR SORTING AND MAINTENANCE OF CELLULAR COMPARTMENTS- CYTOSOL/NUCLEUS TRANSPORT – PROTEIN TRANSLOCATION TO MITOCHONDRION, PEROXYSOMES , ENDOPLASMIC RETICULUM - PEROXYSOMAL DISEASES 4. THE SECRETORY PATHWAY –ENDOPLASMIC RETICULUM: POSTTRANSLATIONAL MODIFICATIONS AND PROTEIN QUALITY CONTROL – MOLECULAR MECHANISMS OF VESICULAR TRANSPORT – DISESSES OF VESICULAR TRAFFICKING - THE GOLGI COMPLEX- EXOCYTOSIS 5. FUNCTIONS AND MAINTENANCE OF THE ENDOSOMAL COMPARTMENT – FAGOCYTOSIS, AUTOPHAGY, RECEPTOR MEDIATED ENDOCYTOSIS - TRANSCYTOSIS - LYSOSOMAL AND ENDOSOMAL DISEASES 6. CYTOSKELETON: INTERMEDIATE FILAMENTS - MECHANISMS OF MICROTUBULES AND ACTIN POLYMERIZATION , MOLECULAR MOTORS CILIA/FLAGELLA -ROLE OF CYTOSKELETON COMPONENTS IN HUMAN DISEASES 7. CELL CYCLE CONTROL - CELLULAR REPRODUCTION: MITOSIS AND MEIOSIS - FERTILIZATION 8. GENETICS PRINCIPLES - MENDELIAN INHERITANCE, INCLUDING MULTIPLE ALLELISM, GENE INTERACTIONS AND SEX-LINKED TRANSMISSION - PEDIGREES PRACTICAL LESSONS: PRESENTATION AND DISCUSSION OF RESEARCH ARTICLES MODULE OF ODONTOSTOMATOLOGY: 1. BIOLOGY, GENETICS AND EVOLUTION APPLIED TO ORAL SYSTEM 2. BIOLOGY AND GENETICS OF DENTAL DISEASES 3. BIOLOGY AND GENETICS OF ORAL AND MAXILLOFACIAL DISEASES 4. MAIN GENETIC ORAL DISEASES 5. BIOLOGY AND GENETICS OF RARE ORAL DISEASES

Contents

LECTURES
1. PROPERTIES OF CELL MEMBRANES
2. AEROBIC RESPIRATION - BIOGENESIS AND MAINTAINANCE OF MITOCHONDRION - MITOCHONDRIAL DISEASES
3. INTRACELLULAR SORTING AND MAINTENANCE OF CELLULAR COMPARTMENTS- CYTOSOL/NUCLEUS TRANSPORT – PROTEIN TRANSLOCATION TO MITOCHONDRION, PEROXYSOMES , ENDOPLASMIC RETICULUM - PEROXYSOMAL DISEASES
4. THE SECRETORY PATHWAY –ENDOPLASMIC RETICULUM: POSTTRANSLATIONAL MODIFICATIONS AND PROTEIN QUALITY CONTROL – MOLECULAR MECHANISMS OF VESICULAR TRANSPORT – DISESSES OF VESICULAR TRAFFICKING - THE GOLGI COMPLEX- EXOCYTOSIS
5. FUNCTIONS AND MAINTENANCE OF THE ENDOSOMAL COMPARTMENT – FAGOCYTOSIS, AUTOPHAGY, RECEPTOR MEDIATED ENDOCYTOSIS - TRANSCYTOSIS - LYSOSOMAL AND ENDOSOMAL DISEASES
6. CYTOSKELETON: INTERMEDIATE FILAMENTS - MECHANISMS OF MICROTUBULES AND ACTIN POLYMERIZATION , MOLECULAR MOTORS CILIA/FLAGELLA -ROLE OF CYTOSKELETON COMPONENTS IN HUMAN DISEASES
7. CELL CYCLE CONTROL - CELLULAR REPRODUCTION: MITOSIS AND MEIOSIS - FERTILIZATION
8. GENETICS PRINCIPLES - MENDELIAN INHERITANCE, INCLUDING MULTIPLE ALLELISM, GENE INTERACTIONS AND SEX-LINKED TRANSMISSION - PEDIGREES
PRACTICAL LESSONS: PRESENTATION AND DISCUSSION OF RESEARCH ARTICLES
MODULE OF ODONTOSTOMATOLOGY:
1. BIOLOGY, GENETICS AND EVOLUTION APPLIED TO ORAL SYSTEM
2. BIOLOGY AND GENETICS OF DENTAL DISEASES
3. BIOLOGY AND GENETICS OF ORAL AND MAXILLOFACIAL DISEASES
4. MAIN GENETIC ORAL DISEASES
5. BIOLOGY AND GENETICS OF RARE ORAL DISEASES

	Teaching Methods
	LECTURES PRACTICAL LESSONS

	Verification of learning
	ORAL TEST WILL VERIFY THE LEVEL OF KNOWLEDGE AND UNDERSTANDING OF CELL STRUCTURES AND THEIR RELATED FUNCTION AND TEST THE ABILITY TO CORRELATE CELL DYSFUNCTION TO INHERITED OR ACQUIRED HUMAN PATHOLOGIES. The exam grade is expressed in thirtieths. Collegial evaluation of the members of the exam Commission.